Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/99379
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Type: Journal article
Title: Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation
Author: Liang, K.
Coghlan, C.
Bell, S.
Doonan, C.
Falcaro, P.
Citation: Chemical Communications, 2016; 52(3):473-476
Publisher: The Royal Society of Chemistry
Issue Date: 2016
ISSN: 1359-7345
1364-548X
Statement of
Responsibility: 
Kang Liang, Campbell J. Coghlan, Stephen G. Bell, Christian Doonan, and Paolo Falcaro
Abstract: Recent studies have demonstrated that metal-organic frameworks can be employed as protective coatings for enzymes. Two efficient strategies have been reported for the synthesis of such composite materials: biomimetic mineralisation and controlled co-precipitation using polyvinylpyrrolidone. We assessed the relative efficacy of each approach by comparing the thermal stability of encapsulated urease. The resulting data shows that over a range of temperatures biomimetic mineralisation offers superior protection than the co-precipitation method.
Keywords: Zeolites
Organometallic Compounds
Imidazoles
Urease
Capsules
Drug Stability
Biomimetics
Temperature
Chemical Precipitation
Rights: ©The Royal Society of Chemistry 2016
DOI: 10.1039/C5CC07577G
Appears in Collections:Aurora harvest 3
Chemistry and Physics publications

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