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https://hdl.handle.net/2440/99379
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Type: | Journal article |
Title: | Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation |
Author: | Liang, K. Coghlan, C. Bell, S. Doonan, C. Falcaro, P. |
Citation: | Chemical Communications, 2016; 52(3):473-476 |
Publisher: | The Royal Society of Chemistry |
Issue Date: | 2016 |
ISSN: | 1359-7345 1364-548X |
Statement of Responsibility: | Kang Liang, Campbell J. Coghlan, Stephen G. Bell, Christian Doonan, and Paolo Falcaro |
Abstract: | Recent studies have demonstrated that metal-organic frameworks can be employed as protective coatings for enzymes. Two efficient strategies have been reported for the synthesis of such composite materials: biomimetic mineralisation and controlled co-precipitation using polyvinylpyrrolidone. We assessed the relative efficacy of each approach by comparing the thermal stability of encapsulated urease. The resulting data shows that over a range of temperatures biomimetic mineralisation offers superior protection than the co-precipitation method. |
Keywords: | Zeolites Organometallic Compounds Imidazoles Urease Capsules Drug Stability Biomimetics Temperature Chemical Precipitation |
Rights: | ©The Royal Society of Chemistry 2016 |
DOI: | 10.1039/C5CC07577G |
Published version: | http://dx.doi.org/10.1039/c5cc07577g |
Appears in Collections: | Aurora harvest 3 Chemistry and Physics publications |
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