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dc.contributor.advisorPeters, Micah-
dc.contributor.advisorWhite, Sarahlouise-
dc.contributor.advisorStern, Cindy-
dc.contributor.authorTilley, Erica-
dc.description.abstractBackground: Progressive supranuclear palsy is an adult onset neurodegenerative condition. Progressive supranuclear palsy is an aggressive condition associated with a continual loss of function and commonly, death due to aspiration pneumonia. Currently there is no cure, and dopaminergic medications have limited symptomatic benefit for patients. Physiotherapy, occupational therapy, and speech therapy strategies to optimize independence and function are important and show promising effectiveness in practice. Mobility, speech and swallowing problems are some of the most commonly experienced symptoms and are experienced across all stages of the disease. Objectives:This systematic review aimed to identify and examine the effectiveness of physical, occupational, and speech therapy interventions in the symptomatic management of progressive supranuclear palsy. Inclusion criteria: This review included participants with progressive supranuclear palsy as per the National Institute for Neurological Disorders and Stroke and the Society of Progressive Supranuclear Palsy criteria, aged over 40 years of age from all community and clinical settings. This review included studies evaluating any physical, occupational or speech therapy interventions that addressed mobility, vision, swallowing, communication or cognitive/neuropsychiatric difficulties experienced by patients with progressive supranuclear palsy compared with usual care and/or baseline measurements. Outcomes of interest included the degree of change, or no change in common symptoms including mobility, vision, swallowing, communication and cognition. All types of quantitative study designs were eligible for inclusion. Methods: A three-step search strategy was utilized to identify published and unpublished English language studies from between 1996 and 2014 from 11 databases. Methodological appraisal was conducted by two independent reviewers using standardized instruments and relevant data was extracted from included papers using standardized data extraction tools and presented in narrative form due to heterogeneity of interventions. Results: Six studies of varying methodological quality and small sample sizes were included. No occupational therapy or speech therapy interventions were identified. Five studies examined physiotherapy rehabilitation programs and one study examined non-invasive brain stimulation. There is preliminary evidence to support the use of various physiotherapy rehabilitation programs. Physiotherapy rehabilitation programs that combine a dynamic antigravity postural system and a vibration sound system or combine balance and posture exercises with audiobiofeedback appear to improve balance. Combined balance and eye movement training appear to improve stance time and gait speed. Balance training appears to improve step length. Balance and eye movement training may improve vertical gaze fixation and gaze error scores. Balance and posture exercises with audiobiofeedback may improve cognition and communication aspects of quality of life. Conclusion: Research into the effectiveness of allied health therapeutic interventions for progressive supranuclear palsy symptoms is in its infancy with what can be understood as preliminary evidence for the effectiveness of a number of physiotherapy interventions. High quality studies with large sample sizes are needed. Further research is urgently required to both add further evidence to these results and to identify and investigate effective interventions including occupational therapy and speech therapy interventions to manage mobility, vision, swallowing, communication and cognitive/neuropsychiatric symptoms associated with this devastating condition.en
dc.subjectoccupational therapyen
dc.subjectspeech pathologyen
dc.subjectspeech therapyen
dc.subjectsystematic reviewen
dc.titleThe effectiveness of allied health therapy in the symptomatic management of progressive supranuclear palsy: a systematic reviewen
dc.contributor.schoolJoanna Briggs Instituteen
dc.provenanceThis electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exceptions. If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at:
dc.description.dissertationThesis (M.Clin.Sc.) -- University of Adelaide, Joanna Briggs Institute, 2016.en
Appears in Collections:Research Theses

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