Maternal and neonatal outcomes following induction of labor: a cohort study
Date
2012
Authors
Grivell, R.
Reilly, A.
Oakey, H.
Chan, A.
Dodd, J.
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Journal article
Citation
Acta Obstetricia et Gynecologica Scandinavica, 2012; 91(2):198-203
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Rosalie M. Grivell, Aimee J. Reilly, Helena Oakey, Annabelle Chan & Jodie M. Dodd
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Abstract
Objective. To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age and also by onset of labor. Design. Cohort study. Setting. A state-wide perinatal outcome database. Population. 28 626 women with spontaneous onset of labor, induction of labor for recognized indications and induction of labor for non-recognized indications. Methods. Cohort study utilizing a validated dataset comparing outcomes with type of onset of labor using a log binomial model. Main outcome measures. Cesarean section, assisted vaginal birth, importantmeasures ofmaternal and neonatal morbidity. Results. Induction of labor for non-recognized indications was associated with a significantly increased risk of a range of outcomes, including cesarean section (RR 1.67, 95%CI 1.55–1.80). The lowest risk of adversematernal and infant outcome occurred with birth between 38 and 39 weeks and with the spontaneous onset of labor. Conclusions. Induction of labor for non-recognized indications at term is associated with an increased risk of adverse outcomes. Caution is warranted with a liberal policy of induction of labor at term in an otherwise uncomplicated pregnancy.
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© 2011 Nordic Federation of Societies of Obstetrics and Gynecology