3D printing in suspension baths: keeping the promises of bioprinting afloat
Date
2020
Authors
McCormack, A.
Highley, C.B.
Leslie, N.R.
Melchels, F.P.W.
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Journal article
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Trends in Biotechnology, 2020; 38(6):584-593
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Abstract
Extrusion-based 3D printers have been adopted in pursuit of engineering functional tissues through 3D bioprinting. However, we are still a long way from the promise of fabricating constructs approaching the complexity and function of native tissues. A major challenge is presented by the competing requirements of biomimicry and manufacturability. This opinion article discusses 3D printing in suspension baths as a novel strategy capable of disrupting the current bioprinting landscape. Suspension baths provide a semisolid medium to print into, voiding many of the inherent flaws of printing onto a flat surface in air. We review the state-of-the-art of this approach and extrapolate toward future possibilities that this technology might bring, including the fabrication of vascularized tissue constructs.
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Copyright 2019 The Author(s). This is an open access article under the CC BY license. (https://creativecommons.org/licenses/by/4.0/)