Bioinformatics and protein engineering; presenting a few applications employed in our labs
Date
2011
Authors
Ebrahimi, M.
Ebrahimie, E.
Tahmasebi, A.
Sarvestani, N.
Deihimi, T.
Editors
Mahadevan, V.
Yu, W.
Zhou, J.
Yu, W.
Zhou, J.
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Conference paper
Citation
2009 International Conference on Machine Learning and Computing, vol 3, 2011 / pp.516-520
Statement of Responsibility
Mansour Ebrahimi, Esmaeil Ebrahimie, Ahmad Tahmasebi, Narjes Rahpeyma Sarvestani, Tahereh Deihimi
Conference Name
International Conference on Machine Learning and Computing (2009 : Perth, Western Australia)
Abstract
Bioinformatics uses various algorithms and methods to explorer huge amount of biological data in order to help us to understand biological mechanisms. In our labs research groups use bioinformatics tools to investigate and understand why some biological processes are working and what are the most important features contributing to their functions. Of special importance to our researchers are some enzymes and proteins responsible for salinity and drought stresses and thermostability. Different approaches have been employed but they can be classified as follows: a. statistical analyses to understand the significant differences among normal and desired proteins (halophilic or thermostable), b. feature selection algorithms to define the most important features contributing to desired protein activities, c. neural network modelings and tools to train and test different networks in order to correlate between features and protein characteristics and use these networks to predict desired abilities. The results of some research groups have been presented briefly here.
School/Discipline
Dissertation Note
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© (2011) IACSIT Press, Singapore