A one year high protein, low fat weight loss diet improves body composition and cardiometabolic risk factors in overweight males
Date
2012
Authors
Wycherley, T.
Brinkworth, G.
Clifton, P.
Noakes, M.
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Conference item
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The FASEB Journal, 2012, vol.26, iss.1 Supplement 387.2, pp.1-1
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Experimental Biology Meeting (21 Apr 2012 - 25 Apr 2012 : San Diego, USA)
Abstract
Objective: To evaluate the effects of two energy matched, low fat, hypocaloric diets differing in carbohydrate to protein ratio, on body composition and cardiometabolic health outcomes in overweight males. Methods: 120 males (age 50.8±9.3 yrs, BMI 33.0±3.9 kg/m2) were randomly assigned to a low fat, isocaloric, energy restricted diet (7MJ/day) with either high protein (HP; Pro:Carb:Fat % energy, 35:40:25) or standard protein (SP; 17:58:25). Body weight, body composition, and cardiometabolic risk factors were assessed at baseline and after one year. Results: 68 participants completed the study (HP n=33; SP n=35). Both groups experienced similar reductions in body weight (HP −12.3±8.0 kg [−12%]; SP −10.9±8.6 kg [−11%]) and fat mass (HP − 9.9±6.0 kg [−27%]; SP −7.3±5.8 kg [−22%]), P>0.11 time x group. Participants who consumed the HP diet lost less fat free mass (−2.6±3.7 kg [−4%] vs. −3.8±4.7 kg [−6%]), P<0.01. Both groups experienced a similar overall increase in HDL cholesterol (8%) and reductions in total cholesterol (−7%), LDL cholesterol (−9%), triglycerides (−24%), glucose (−3%), insulin (−38%), blood pressure (−7/−12%) and C-reactive protein (−29%), P≥0.14. Conclusions: In overweight and obese males, a HP and SP diet similarly reduce body weight and improve cardiometabolic health outcomes. A HP diet was more effective for improving body composition.
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Copyright 2012 the Federation of American Societies for Experimental Biology