Systematic evolution of ligands by exponential enrichment: tissue selex

dc.contributor.assignee	NeXstar Pharmaceuticals, Inc.
dc.contributor.author	Jensen, K.B.
dc.contributor.author	Chen, H.
dc.contributor.author	Morris, K.N.
dc.contributor.author	Stephens, A.
dc.contributor.author	Gold, L.
dc.date.issued	1998
dc.description	Publication number US5712375 A Publication type Grant Application number US 08/434,001 Publication date Jan 27, 1998 Filing date May 3, 1995 Priority date Jun 11, 1990
dc.description.abstract	This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.
dc.description.statementofresponsibility	Inventors: Jensen Kirk, Chen Hang, Morris Kevin N., Stephens Andrew, Gold Larry. Assignee: NeXstar Pharmaceuticals, Inc. Agents: Swanson & Bratschun LLC
dc.identifier.orcid	Jensen, K.B. [0000-0002-2084-1734]
dc.identifier.patent	US5712375
dc.identifier.uri	http://hdl.handle.net/2440/87909
dc.language.iso	en
dc.source.uri	https://www.google.com/patents/US5712375
dc.title	Systematic evolution of ligands by exponential enrichment: tissue selex
dc.type	Patent
pubs.publication-status	Published

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