Fully endoscopic transsphenoidal resection of pituitary tumors: Technique and results

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dc.contributor.authorUren, B.
dc.contributor.authorVrodos, N.
dc.contributor.authorWormald, P.
dc.date.issued2007
dc.description.abstract<h4>Background</h4>The aim of this study was to describe our two-surgeon fully endoscopic approach to pituitary surgery and to report results in terms of tumor remission, improvement in vision, and complications. A retrospective chart review was performed.<h4>Methods</h4>Our prospectively recorded surgical database was searched for all endoscopic transsphenoidal procedures between January 2001 and December 2005. Those patients who had surgery had their medical charts reviewed and presenting symptoms and signs, lesion characteristics, endocrine investigations, operative details, complications, and treatment outcomes recorded.<h4>Results</h4>Thirty-two patients were included in the study. Twenty-three patients had macroadenomas, five patients had microadenomas, and four patients had other pathologies. Most patients with macroadenomas had significant supra- or parasellar extension. Of the 14 patients who had visual loss at presentation, 13 had postoperative improvement. Two patients had postoperative cerebrospinal fluid leaks, which were successfully treated endoscopically. Eight patients required some form of hormone replacement after surgery. After a mean follow-up of 31 months, the overall remission rate for patients with macroadenomas was 82% and for patients with microadenomas was 100%.<h4>Conclusion</h4>The fully endoscopic transsphenoidal approach provides excellent visualization for tumor resection and results in acceptable remission rates.
dc.identifier.citationAmerican Journal of Rhinology and Allergy, 2007; 21(4):510-514
dc.identifier.doi10.2500/ajr.2007.21.3059
dc.identifier.issn1945-8924
dc.identifier.issn1050-6586
dc.identifier.orcidWormald, P. [0000-0001-7753-7277]
dc.identifier.urihttp://hdl.handle.net/2440/42934
dc.language.isoen
dc.publisherOcean Side Publications Inc
dc.source.urihttps://doi.org/10.2500/ajr.2007.21.3059
dc.subjectHumans
dc.subjectAdenoma
dc.subjectPituitary Neoplasms
dc.subjectEndoscopy
dc.subjectRemission Induction
dc.subjectNeurosurgical Procedures
dc.subjectRetrospective Studies
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectFemale
dc.subjectMale
dc.titleFully endoscopic transsphenoidal resection of pituitary tumors: Technique and results
dc.typeJournal article
pubs.publication-statusPublished

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