Optical biosensing for label-free cellular studies

Date

2014

Authors

Mejard, R.
Griesser, H.J.
Thierry, B.

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Journal article

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TrAC. Trends in analytical chemistry, 2014; 53:178-186

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Abstract

Optical biosensors such as waveguides and surface-plasmon resonance (SPR) sensors have found numerous applications in biomolecular sciences. We provide an overview of these technologies in relation to the specific requirements of label-free and high-throughput cellular studies. We dedicate specific emphasis to SPR-based biosensors and recent developments particularly suitable for cellular studies, such as long-range SPR. We discuss the advantages and the disadvantages of the most successful optical-sensing technologies, and potential approaches in the next generation of optical technologies.

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Copyright 2013 Elsevier

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