Sonochemical degradation of the persistent pharmaceutical carbamazepine

Date

2013

Authors

Tran, N.
Drogui, P.
Zaviska, F.A.
Brar, S.K.

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Journal article

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Journal of Environmental Management, 2013; 131:25-32

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Abstract

The objective of this work was to evaluate the potential of a sonochemical oxidation process for the degradation of carbamazepine (CBZ). Several factors, such as electrical power, treatment time, pH and initial concentration of CBZ were investigated. Using a 24 factorial matrix, the best performance for CBZ degradation (90.1% of removal) was obtained with an electrical power of 40 W, a treatment time of 120 min and an initial pH of 10.0 imposed in the presence of 6.0 mg L−1 of CBZ. The treatment time and the calorimetric power were the most influential parameters on the degradation rate of CBZ. Subsequently, the optimal experimental parameters for CBZ degradation were investigated using central composite design. The sonochemical oxidation process, applied under optimal operating conditions (at an electrical power of 43 W for 116 min), oxidized 86 and 90% of the initial CBZ concentration of 5.62 mg L−1 and 8.05 μg L−1, respectively. During the sonochemical process, CBZ was primarily transformed into anthranilic acid and acridine.

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Data source: Supplementary material, https://doi.org/10.1016/j.jenvman.2013.09.027

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Copyright 2013 Elsevier

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