Metal–organic framework coatings as cytoprotective exoskeletons for living cells
Date
2016
Authors
Liang, K.
Richardson, J.
Cui, J.
Caruso, F.
Doonan, C.
Falcaro, P.
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Journal article
Citation
Advanced Materials, 2016; 28(36):7910-7914
Statement of Responsibility
Kang Liang, Joseph J. Richardson, Jiwei Cui, Frank Caruso, Christian J. Doonan and Paolo Falcaro
Conference Name
Abstract
The biomimetic mineralization of metal–organic framework (MOF) material on living cells is reported. ZIF-8 can be crystallized on a living cell surface as an exoskeleton that offers physical protection while allowing transport of essential nutrients, thus maintaining cell viability. The MOF shell prevents cell division, leading to an artificially induced pseudo-hibernation state. Cellular functions can be fully restored upon MOF removal.
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© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim