The exploratory clinical development of tucaresol, an antisickling agent, using a novel surrogate marker

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1995

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Rolan, Paul Edward

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Dept. of Clinical and Experimental Pharmacology

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Thesis (M.D.) -- University of Adelaide, Dept. of Clinical and Experimental Pharmacology, 1995

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Describes the exploratory clinical development of tucaresol, consisting of three studies performed on humans and subsequent in vitro and animal studies investigating the possible effects on the immune system. Demonstrates that rational drug design may be an efficient way of selecting potential therapeutic candidates.
xxi, 265 leaves

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