Effects on (neuro)developmental and behavioral outcome at 2 years of age of induced labor compared with expectant management in intrauterine growth-restricted infants: long-term outcomes of the DIGITAT trial
Date
2012
Authors
van Wyk, L.
Boers, K.
van der Post, J.
van Pampus, M.
van Wassenaer, A.
van Baar, A.
Spaanderman, M.
Becker, J.
Kwee, A.
Duvekot, J.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
American Journal of Obstetrics and Gynecology, 2012; 206(5):406.e1-406.e7
Statement of Responsibility
Linda van Wyk, Kim E. Boers, Joris A.M. van der Post, Maria G. van Pampus, Aleid G. van Wassenaer, Anneloes L. van Baar, Marc E.A. Spaanderdam, Jeroen H. Becker, Anneke Kwee, Johannes J. Duvekot, Henk A. Bremer, Friso M.C. Delemarre, Kitty W.M. Bloemenkamp, Christianne J.M. de Groot, Christine Willekes, Frans J.M.E. Roumen, Jan M.M. van Lith, Ben W.J. Mol, Saskia le Cessie, Sicco A. Scherjon, for the DIGITAT Study Group
Conference Name
Abstract
Objective: We sought to study long-term (neuro)developmental and behavioral outcome of pregnancies complicated by intrauterine growth restriction at term in relation to induction of labor or an expectant management. Study Design: Parents of 2-year-old children included in the Disproportionate Intrauterine Growth Intervention Trial at Term (DIGITAT) answered the Ages and Stages Questionnaire (ASQ) and Child Behavior Checklist (CBCL). Results: We approached 582 (89.5%) of 650 parents. The response rate was 50%. Of these children, 27% had an abnormal score on the ASQ and 13% on the CBCL. Results of the ASQ and the CBCL for the 2 policies were comparable. Low birthweight, positive Morbidity Assessment Index score, and admission to intermediate care increased the risk of an abnormal outcome of the ASQ. This effect was not seen for the CBCL. Conclusion: In women with intrauterine growth restriction at term, neither a policy of induction of labor nor expectant management affect developmental and behavioral outcome when compared to expectant management.
School/Discipline
Dissertation Note
Provenance
Description
Presented at the 32nd annual meeting of the Society for Maternal-Fetal Medicine, Dallas, TX, Feb. 6-11, 2012.
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Rights
© 2012 Mosby, Inc. All rights reserved.