A phase II trial of cisplatin and interferon alpha 2b in patients with advanced bladder cancer.

Date

1997

Authors

Parnis, F.
Olver, I.
Sandeman, T.
Bishop, J.
Laidlaw, C.

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American Journal of Clinical Oncology: Cancer Clinical Trials, 1997; 20(3):319-321

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Abstract

Twenty-two patients with advanced transitional cell bladder cancer were treated in a phase II trial exploring the possible synergy of cisplatin and interferon alpha 2b. Of the 20 evaluable patients, 7 (35%) had a partial response to the treatment, and only 6 patients were able to complete the full planned six cycles of treatment. Response rates, duration of responses, and overall survival of our patients are not superior to those expected by cisplatin alone.

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