Comparative study on 1D (VP1) region of foot and mouth disease virus (Type A strain) among different isolates: Khorasan Razavi isolate and other Iranian and neighboring countries isolates
Date
2010
Authors
Zibaei, S.
Keivanfar, H.
Rabbani, M.
Hemmatzadeh, F.
Kianizade, M.
Fathi najafi, M.
Farhodi, M.
Hemmati, M.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Journal of Veterinary Research, 2010; 65(3):199-202
Statement of Responsibility
Saied Zibaei, Hadi Keivanfar, Mohammad Rabbani, Farhid Hematzadeh, Mehdi Kianizade, Mohsen Fathi najafi, Majid Farhodi and Mohammad Hemmati
Conference Name
Abstract
Foot-and-mouth disease (FMD) is one of the most important virus disease in farm animals. Types O, A and Asia1 FMD virus have been endemic in Iran. In these study, samples from suspected livestock were analyzed by RT-PCR experiment. The number of 702 nucleotides determined at 1D -2B region of type A strain isolated from Khorasan Razavi province sequenced and compared with that of other reported isolates type A from Iran and neighboring countries.The results show that field isolated type A has about 89% similarity with other reported isolates type A from Iran and neighboring countries. Furthermore, this virus shows the most similarity with A/IRN/1/87(Samuel). Phylogenitic analysis revealed that virus was closely related to A22-Iraq/99 and A/IRN/iso/105 that rest in the same lineage. The data showed high similarity between type A viruses involved in the Khorasan Razavi province and A/IRN/87v (vaccine strain); so that it can be concluded that the vaccine can produce prophylactic antibody against this virus.
School/Discipline
Dissertation Note
Provenance
Description
Access Status
Rights
© All rights reserved. University of Tehran