Ketoprofen-LDH nanohybrid for transdermal drug delivery system
Date
2012
Authors
Park, M.C.
Kim, H.
Park, D.H.
Yang, J.H.
Choy, J.H.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Bulletin of the Korean Chemical Society, 2012; 33(6):1827-1828
Statement of Responsibility
Conference Name
Abstract
Two dimensional inorganic matrix have attracted a great attention due to their medical applications in storage, delivery,and controlled-release of drug, gene and cosmeceuticals. Among inorganic layered materials, layered double hydroxides (LDHs) have been systematically studied to design bio-inorganic nanohybrids, since the biocompatible LDHs are considered as efficient nano-reservoir for stabilizing fragile bio and organic molecules as well as nano-carrier with controlled release of intercalated pharmaceutical,nutritional and cosmetic molecules.
The aim of this study was, therefore, subjected to the intercalation of KP drug into LDH to induce the controlled release property, and the structural and chemical characterizations of the KP-LDH nanohybrid. And at the same time, an attempt was made to figure out the in-vitro release behavior of the KP-LDH and its transdermal delivery efficacy in topical application on the bases of mouse-skin permeability experiment.
School/Discipline
Dissertation Note
Provenance
Description
Access Status
Rights
Copyright 2015 Korean Chemical Society