ST/T wave changes during acute coronary syndrome presentation in patients with the coronary slow flow phenomenon
Date
2011
Authors
Cutri, N.
Zeitz, C.
Kucia, A.
Beltrame, J.
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Journal article
Citation
International Journal of Cardiology, 2011; 146(3):457-458
Statement of Responsibility
Natalie Cutri, Christopher Zeitz, Angela M. Kucia, John F. Beltrame
Conference Name
Abstract
The coronary slow flow phenomenon (CSFP) is an angiographic finding characterised by delayed opacification of the distal vasculature in the absence of obstructive epicardial coronary artery disease (CAD). It is associated with coronary microvascular dysfunction however the consistent presence of myocardial ischaemia has been elusive. In particular, transmyocardial lactate studies and coronary/myocardial flow reserve studies have not shown significant abnormalities.
The lack of objective evidence of ischaemia in these studies may reflect both methodological limitations and the variable course of the CSFP. It often initially presents as an acute coronary syndrome (ACS), yet most pathophysiological studies were undertaken during its variable chronic phase. Continuous 12-lead ST/T wave monitoring is an established method for detecting ischaemia that is clinically-validated and predictive of cardiac outcomes.
The objective of this study was to ascertain the clinical presence of myocardial ischaemia in the CSFP by determining the frequency of significant ST/T wave changes during its ACS presentation.
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Data source: Tables, https://doi.org/10.1016/j.ijcard.2010.10.120
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Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.