A phase-segregated model for plant cell culture: the effect of cell volume fraction

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dc.contributor.authorZhang, W.
dc.contributor.authorFurusaki, S.
dc.contributor.authorMiddelberg, A.
dc.date.issued1998
dc.description.abstractPlant cells are characterized by low water content, so the fraction of cell volume (volume fraction) in a vessel is large compared with other cell systems, even if the cell concentrations are the same. Therefore, concentration of plant cells should preferably be expressed by the liquid volume basis rather than by the total vessel volume basis. In this paper, a new model is proposed to analyze behavior of a plant cell culture by dividing the cell suspension into the biotic- and abiotic-phases. Using this model, we analyzed the cell-growth and the alkaloid production by Catharanthus roseus. Large errors in the simulated results were observed if the phase-segregation was not considered.
dc.description.statementofresponsibilityWei Zhang, Shintaro Furusaki, Anton P. J. Middelberg
dc.identifier.citationJournal of Chemical Engineering of Japan, 1998; 31(3):469-474
dc.identifier.doi10.1252/jcej.31.469
dc.identifier.issn0021-9592
dc.identifier.issn1881-1299
dc.identifier.urihttp://hdl.handle.net/2440/857
dc.language.isoen
dc.publisherTAYLOR & FRANCIS LTD
dc.rights© 1998 The Society of Chemical Engineers, Japan
dc.source.urihttps://doi.org/10.1252/jcej.31.469
dc.subjectPlant Cell Culture, Phase-Segregated, Modeling, Cell Volume Fraction (CVF), Structured Model
dc.titleA phase-segregated model for plant cell culture: the effect of cell volume fraction
dc.typeJournal article
pubs.publication-statusPublished

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