Risk of traumatic intracranial haemorrhage in children with bleeding disorders
Date
2020
Authors
Bressan, S.
Monagle, P.
Dalziel, S.R.
Borland, M.L.
Phillips, N.
Kochar, A.
Lyttle, M.D.
Cheek, J.A.
Neutze, J.
Oakley, E.
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Journal article
Citation
Journal of Paediatrics and Child Health, 2020; 56(12):1891-1897
Statement of Responsibility
Silvia Bressan, Paul Monagle, Stuart R Dalziel, Meredith L Borland, Natalie Phillips, Amit Kochar, Mark D Lyttle, John A Cheek, Jocelyn Neutze, Ed Oakley, Sarah Dalton, Yuri Gilhotra, Stephen Hearps, Jeremy Furyk, Franz E Babl [on behalf of the Paediatric Research in Emergency Departments International Collaborative, (PREDICT)]
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Abstract
Aim: To assess computerised tomography (CT) use and the risk of intracranial haemorrhage (ICH) in children with bleeding disorders following a head trauma. Methods: Design: Multicentre prospective observational study. Setting: 10 paediatric emergency departments (ED) in Australia and New Zealand. Patients: Children <18 years with and without bleeding disorders assessed in ED following head trauma between April 2011 and November 2014. Interventions: Data collection of patient characteristics, management and outcomes. Main Outcome Measures: Rate of CT use and frequency of ICH on CT. Results: Of 20 137 patients overall, 103 (0.5%) had a congenital or acquired bleeding disorder. CT use was higher in these patients compared with children without bleeding disorders (30.1 vs. 10.4%; rate ratio 2.91 95% CI 2.16-3.91). Only one of 31 (3.2%) children who underwent CT in the ED had an ICH. This patient rapidly deteriorated in the ED on arrival and required neurosurgery. None of the patients with bleeding disorders who did not have a CT obtained in the ED or had an initial negative CT had evidence of ICH on follow up. Conclusions: Although children with a bleeding disorder and a head trauma more often received a CT scan in the ED, their risk of ICH seemed low and appeared associated with post-traumatic clinical findings. Selective CT use combined with observation may be cautiously considered in these children based on clinical presentation and severity of bleeding disorder.
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© 2020 Paediatrics and Child Health Division (The Royal Australasian College of Physicians)