Does a Mediterranean diet reduce the mortality risk associated with diabetes: evidence form the Melbourne Collaborative Cohort Study

Hodge, A.M.; English, D.; Itsiopoulos, C.; O'Dea, K.; Giles, G.

doi:10.1016/j.numecd.2010.10.014

Does a Mediterranean diet reduce the mortality risk associated with diabetes: evidence form the Melbourne Collaborative Cohort Study

Date

2011

Authors

Hodge, A.M.

English, D.

Itsiopoulos, C.

O'Dea, K.

Giles, G.

Type:

Journal article

Citation

Nutrition, Metabolism and Cardiovascular Diseases, 2011; 21(9):733-739

DOI

10.1016/j.numecd.2010.10.014

Abstract

Background and aims: Diabetes is a risk factor for cardiovascular disease (CVD), yet southern European migrants to Australia with high rates of type 2 diabetes have relatively low CVD mortality. Our aim was to determine whether a Mediterranean style diet could reduce mortality in people with diabetes. Methods and results: Participants included 16,610 males and 23,860 females from the Melbourne Collaborative Cohort Study; 25% were born in Greece or Italy, and 2150 had previously been diagnosed with diabetes or had elevated blood glucose at baseline (1990-94). Data on demographic, behavioral and physical risk factors were also collected. A personal Mediterranean Diet Score (MDS) was calculated using data from a validated 121-item food frequency questionnaire. Total and CVD mortality data were available up to 2003.Diabetes (new and known) at baseline, was associated with total mortality (men HR 1.43, 95%CI 1.26-1.62; women HR 1.86 95%CI 1.58-2.18), and CVD mortality (men HR 1.53, 95%CI 1.21-1.94; women HR 2.10 95%CI 1.48-2.97) in multivariate models. There was no evidence that glucose tolerance modified the associations between MDS and total or CVD mortality (p interaction all > 0.16). The HRs for total mortality per unit of MDS were 0.96 (95% CI 0.93-0.99) in men and 0.94 (95% CI 0.92-0.97) in women. The HRs for CVD mortality per unit of MDS were 0.94 (95% CI 0.89-0.99) in men and 0.94 (95% CI 0.87-1.01) in women. Conclusion: Our results add to the evidence supporting the benefit of a Mediterranean style diet for people with type 2 diabetes.

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https://doi.org/10.1016/j.numecd.2010.10.014

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https://hdl.handle.net/1959.8/118910

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Does a Mediterranean diet reduce the mortality risk associated with diabetes: evidence form the Melbourne Collaborative Cohort Study

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