A life course approach to cardiovascular aging

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dc.contributor.authorHardy, R.
dc.contributor.authorLawlor, D.A.
dc.contributor.authorKuh, D.
dc.date.issued2015
dc.description.abstractA life course approach in epidemiology investigates the biological, behavioral and social pathways that link physical and social exposures and experiences during gestation, childhood, adolescence and adult life, and across generations, to later-life health and disease risk. We illustrate how a life course approach has been applied to cardiovascular disease, highlighting the evidence in support of the early origins of disease risk. We summarize how trajectories of cardiometabolic risk factors change over the life course and suggest that understanding underlying 'normal' or 'healthy' trajectories and the characteristics that drive deviations from such trajectories offer the potential for early prevention and for identifying means of preventing future disease.
dc.description.statementofresponsibilityRebecca Hardy, Debbie A Lawlor and Diana Kuh
dc.identifier.citationFuture Cardiology, 2015; 11(1):101-113
dc.identifier.doi10.2217/fca.14.67
dc.identifier.issn1479-6678
dc.identifier.issn1744-8298
dc.identifier.orcidLawlor, D.A. [0000-0002-6793-2262]
dc.identifier.urihttp://hdl.handle.net/2440/122694
dc.language.isoen
dc.publisherFuture Science Group
dc.rights© Rebecca Hardy, Diana Kuh, Debbie Lawler
dc.source.urihttps://doi.org/10.2217/fca.14.67
dc.subjectAdiposity; birth weight; blood pressure; cardiovascular disease; cohort studies; glucose; life course; lipids; longitudinal modeling; social inequalities
dc.titleA life course approach to cardiovascular aging
dc.typeJournal article
pubs.publication-statusPublished

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