A study of the molecular and biological characteristics of ovine interleukin-12 / Sarah Jane Swinburne.
Date
2000
Authors
Swinburne, Sarah Jane
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Thesis
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Abstract
Interleukin-12 (IL-12) is a heterodimeric cytokine composed of two disulphide-linked subunits, p35 and p40, which form biologically active p70. IL-12 is able to induce IFN-y production from T and NK cells, and promote the proliferation of mitogen-activated T cells. It is thought that IL-12 may be an important cytokine in the initiation and progression of allograft destruction. This thesis describes the characterisation of ovine IL-12.
School/Discipline
Dept. of Medicine
Dissertation Note
Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 2000
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Description
Bibliography: leaves 172-214.
214 leaves, [41] leaves of plates : ill. (some col.) ; 30 cm.
214 leaves, [41] leaves of plates : ill. (some col.) ; 30 cm.