A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

Date

2009

Authors

Ma, M.
Karas, J.
White, J.
Scanlon, D.
Donnelly, P.

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Journal article

Citation

Chemical Communications, 2009; 14(22):3237-3239

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Michelle T. Ma, John A. Karas, Jonathan M. White, Denis Scanlon and Paul S. Donnelly

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Abstract

A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr3]- octreotate and [Lys3]-bombesin) and the conjugates radiolabelled with copper-64.

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© The Royal Society of Chemistry 2009

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