Current gaps in knowledge and future research directions for Aboriginal and Torres Strait Islander children with cancer

Date

2025

Authors

Truong, A.
Williams-Tucker, K.
Narkle, A.
Slicer, E.
Chapman, J.E.
Lawler, J.
Kotecha, R.S.
Dholaria, H.
Clark, J.R.
Brown, A.

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Medical Journal of Australia, 2025; 222(10):524-528

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<jats:title>Summary</jats:title><jats:p> <jats:list list-type="bullet"> <jats:list-item><jats:p>Paediatric cancer is the leading cause of disease‐related death in Australian children. Limited research focuses on cancer in Aboriginal and Torres Strait Islander children.</jats:p></jats:list-item> <jats:list-item><jats:p>Although there appears to be a lower incidence of cancer overall in Aboriginal and Torres Strait Islander children compared with non‐Indigenous children, a high proportion of Aboriginal and Torres Strait Islander children are diagnosed with acute myeloid leukaemia.</jats:p></jats:list-item> <jats:list-item><jats:p>Five‐year overall survival is lower for many cancer types in Aboriginal and Torres Strait Islander children.</jats:p></jats:list-item> <jats:list-item><jats:p>There is a need for Indigenous‐specific research focused on molecular and genetic profiles, pharmacogenomics and survivorship, both within Australia and globally.</jats:p></jats:list-item> <jats:list-item><jats:p>Future research in this space should be co‐designed and led by Aboriginal and Torres Strait Islander communities; alongside clinicians, researchers and services to ensure that the priorities of Aboriginal and Torres Strait Islander people are met.</jats:p></jats:list-item> </jats:list> </jats:p>

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Copyright 2025 the Author(s). this is an Open Access article under the license Attribution-Non Commercial 4.0 International (https://creativecommons.org/licenses/by-nc/4.0/)

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