The use of collective variables and enhanced sampling in the simulations of existing and emerging microporous materials

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2024

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Stracke, K.
Evans, J.D.

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Journal article

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Nanoscale, 2024; 16(19):9186-9196

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Konstantin Stracke and Jack D. Evans

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Abstract

Microporous materials, including zeolites, metal–organic frameworks, and cage compounds, offer diverse functionalities due to their unique dynamics and guest confinement properties. These materials play a significant role in separation, catalysis, and sensing, but their complexity hinders exploration using traditional atomistic simulations. This review explores collective variables (CVs) paired with enhanced sampling as a powerful approach to enable efficient investigation of key features in microporous materials. We highlight successful applications of CVs in studying adsorption, diffusion, phase transitions, and mechanical properties, demonstrating their crucial role in guiding material design and optimisation. The future of CVs lies in integration with techniques like machine learning, allowing for enhanced efficiency and accuracy. By tailoring CVs to specific materials and developing multi-scale approaches we can further unlock the intricacies of these fascinating materials. Simulations are a cornerstone in unravelling the complexities of microporous materials and are crucial for our future understanding.

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© The Royal Society of Chemistry 2024

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