Metachromatic leukodystrophy : the role of non-pathogenic sequence variants in the causation of disease / John Steven Harvey.

Date

1996

Authors

Harvey, John Steven

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Abstract

The objectives of this project are to investigate the development of metachromatic leukodystrophy (MLD) in the patient population referred to the Women's and Children's Hospital to gain further insight into the molecular and biochemical defects which cause disease. This study hypothesises that alleles which cause pseudodeficiencies of arylsulphatase A gene (ASA) may play a role in modifying the course of MLD or may be responsible for the development of the disease.

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Dept. of Paediatrics

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Thesis (Ph.D.)--University of Adelaide, Dept. of Paediatrics, 1997?

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Erratum sheet pasted on front end-paper.
Bibliography: p. 220-239.
xxi, 239 p. : ill. ; 30 cm.

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