Recurrence risk of preterm birth in subsequent singleton pregnancy after preterm twin delivery
Date
2012
Authors
Schaaf, J.
Hof, M.
Mol, B.
Abu-Hanna, A.
Ravelli, A.
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Journal article
Citation
American Journal of Obstetrics and Gynecology, 2012; 207(4):279.e1-279.e7
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Jelle M. Schaaf, Michel H.P. Hof, Ben Willem J. Mol, Ameen Abu-Hanna, Anita C.J. Ravelli
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Abstract
Objective: The purpose of this study was to investigate the recurrence risk of preterm birth (<37 weeks' gestation) in a subsequent singleton pregnancy after a previous nulliparous preterm twin delivery. Study Design: We included 1957 women who delivered a twin gestation and a subsequent singleton pregnancy from the Netherlands Perinatal Registry. We compared the outcome of subsequent singleton pregnancy of women with a history of preterm delivery to the pregnancy outcome of women with a history of term twin delivery. Results: Preterm birth in the twin pregnancy occurred in 1075 women (55%) vs 882 women (45%) who delivered at term. The risk of subsequent spontaneous singleton preterm birth was significantly higher after preterm twin delivery (5.2% vs 0.8%; odds ratio, 6.9; 95% confidence interval, 3.1–15.2). Conclusion: Women who deliver a twin pregnancy are at greater risk for delivering prematurely in a subsequent singleton pregnancy.
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© 2012 Mosby, Inc. All rights reserved.