Total synthesis of variolin B

dc.contributor.authorAnderson, Regan Jamesen
dc.contributor.authorMorris, Jonathan Charlesen
dc.contributor.schoolSchool of Chemistry and Physics : Chemistryen
dc.date.issued2001en
dc.description.abstractThe total synthesis of the marine alkaloid variolin B has been achieved in eight steps, starting from commercially available 4-chloro-2-methylthiopyrimidine. The key reaction involves the tandem deoxygenation and cyclization of a triarylmethanol using a combination of triethylsilane and trifluoroacetic acid.en
dc.description.statementofresponsibilityRegan J. Anderson and Jonathan C. Morrisen
dc.description.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/233/description#descriptionen
dc.identifier.citationTetrahedron Letters, 2001; 42(49):8697-8699en
dc.identifier.doi10.1016/S0040-4039(01)01881-0en
dc.identifier.issn0040-4039en
dc.identifier.urihttp://hdl.handle.net/2440/34454
dc.language.isoenen
dc.publisherPergamon / Elsevieren
dc.titleTotal synthesis of variolin Ben
dc.typeJournal articleen

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