Understanding the evolution of multimorbidity: evidences from the North West Adelaide Health Longitudinal Study (NWAHS)

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dc.contributor.authorRuel, G.
dc.contributor.authorLévesque, J.
dc.contributor.authorStocks, N.
dc.contributor.authorSirois, C.
dc.contributor.authorKroger, E.
dc.contributor.authorAdams, R.
dc.contributor.authorDoucet, M.
dc.contributor.authorTaylor, A.
dc.contributor.editorMiranda, J.
dc.date.issued2014
dc.description.abstractOBJECTIVE: The aim of this study is to describe the evolution of multimorbidity. STUDY DESIGN AND SETTING: Data from 1854 South Australians who participated in the North West Adelaide longitudinal Health Study (NWAHS) was collected between baseline (2000-2002) and follow-up (2008-2010). Status for eight chronic diseases (CDs) was determined by biomedical measurement or self-report. Chronic disease (CD) mean age of occurrence and order of appearance was investigated. RESULTS: The prevalence of multimorbidity increased from 32% to 64% during the 7.8±1.1 years of follow-up. The estimated mean age of onset of a new CD was significantly older for hypertension, cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) and younger for hypercholesterolemia, asthma and other mental problem. Hypercholesterolemia was more likely to develop as a first than as a subsequent CD (39%vs.16%, p<0.0001) while CVD (1%vs.5%, p<0.0001), diabetes (5%vs.11%, p<0.001) and COPD (6%vs.16%, p<0.0001) were less likely. The presence of mood disorders at baseline was associated with an increased risk of developing other mental disorders (36%vs.12%, p<0.0001), diabetes (18%vs.9%, p<0.01) and asthma (30%vs.21%, p<0.05). CONCLUSION: Longitudinal data could be used to study the evolution of multimorbidity and could provide information on CDs mean age of occurrence, order of appearance and impact on the development of future CDs.
dc.description.statementofresponsibilityGuillaume Ruel, Jean-Frédéric Lévesque, Nigel Stocks, Caroline Sirois, Edeltraut Kroger, Robert J. Adams, Mariève Doucet, Anne W. Taylor
dc.identifier.citationPLoS ONE, 2014; 9(5):e96291-1-e96291-11
dc.identifier.doi10.1371/journal.pone.0096291
dc.identifier.issn1932-6203
dc.identifier.issn1932-6203
dc.identifier.orcidStocks, N. [0000-0002-9018-0361]
dc.identifier.orcidAdams, R. [0000-0002-7572-0796]
dc.identifier.orcidTaylor, A. [0000-0002-4422-7974]
dc.identifier.urihttp://hdl.handle.net/2440/94816
dc.language.isoen
dc.publisherPublic Library of Science
dc.rights© 2014 Ruel et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.source.urihttps://doi.org/10.1371/journal.pone.0096291
dc.subjectHumans
dc.subjectChronic Disease
dc.subjectMorbidity
dc.subjectPrevalence
dc.subjectLongitudinal Studies
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectSouth Australia
dc.titleUnderstanding the evolution of multimorbidity: evidences from the North West Adelaide Health Longitudinal Study (NWAHS)
dc.typeJournal article
pubs.publication-statusPublished

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