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Barbara, Jeffrey A. J. (Jeffrey Allan J.) Dept. of Medicine 1995 http://hdl.handle.net/2440/18552 Amendments inserted inside front cover. Bibliograpghy: leaves 111-139. xvi, 139, [29] leaves, [10] leaves of plates : ill. ; 30 cm. The in vivo adminstration of Tumour Necrosis Factor-alpha as an antineoplastic agent has been severely restricted by dose-limiting side effects. Human TNF mutants with selective binding to the Human TNF receptors were employed to examine the role of these receptors in the mediation of TNF's cytotoxic and proinflammatory activities. Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1995? 329310 bytes application/pdf en 616.079 20 Tumor necrosis factor Physiological effect. Inflammation Mediators. The mechanism of action of tumour necrosis factor-α / Jeffrey A.J. Barbara. Thesis This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legalsopen.access