Wells, R.Paterson, F.Bacchi, S.Page, A.Baumert, M.Lau, D.H.2023-12-132023-12-132020Journal of Arrhythmia, 2020; 36(3):549-5521880-42761883-2148https://hdl.handle.net/2440/140179First published: 03 March 2020Background: It remains unclear whether brain fog is related to impaired cerebral blood flow (CBF) in postural tachycardia syndrome (POTS) patients. Methods: We assessed CBF in the posterior cerebral artery (PCA) using transcranial Doppler with visual stimuli in 11 POTS and 8 healthy subjects in the seated position, followed by neurocognitive testing. Results: CBF parameters were similar between the two groups. POTS patients demonstrated significantly longer latency in delayed match to sample response time and greater errors in attention switching task. Conclusions: Impaired short-term memory and alertness may underlie the symptom of brain fog in POTS patients, despite normal CBF.en© 2020 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Heart Rhythm Society. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.cerebral blood flow velocity; cognitive dysfunction; neurovascular coupling; postural tachycardia syndrome; transcranial DopplerJournal article10.1002/joa3.123252023-12-12526072Wells, R. [0000-0002-6847-0143]Bacchi, S. [0000-0001-5130-8628]Page, A. [0000-0002-7086-5865]Baumert, M. [0000-0003-2984-2167]Lau, D.H. [0000-0001-7753-1318]