Li, B.Tester, M.Gilliham, M.2017-05-192017-05-192017Trends in Plant Science, 2017; 22(3):236-2481360-13851878-4372http://hdl.handle.net/2440/105288Chloride (Cl-) is an essential plant nutrient but under saline conditions it can accumulate to toxic levels in leaves; limiting this accumulation improves the salt tolerance of some crops. The rate-limiting step for this process - the transfer of Cl- from root symplast to xylem apoplast, which can antagonize delivery of the macronutrient nitrate (NO3-) to shoots - is regulated by abscisic acid (ABA) and is multigenic. Until recently the molecular mechanisms underpinning this salt-tolerance trait were poorly defined. We discuss here how recent advances highlight the role of newly identified transport proteins, some that directly transfer Cl- into the xylem, and others that act on endomembranes in 'gatekeeper' cell types in the root stele to control root-to-shoot delivery of Cl-.en© 2016 Elsevier Ltd. All rights reserved.ALMT9CCCGmSALT3NPF2.4SLAH1long-distance transportJournal article003006240210.1016/j.tplants.2016.12.0040003978371000082-s2.0-85013634449283562Gilliham, M. [0000-0003-0666-3078]