Chen, Z.Mallavarapu, M.Naidu, R.2025-12-172025-12-172007Talanta, 2007; 73(5):948-9520039-9140https://hdl.handle.net/1959.8/51692When inductively coupled plasma mass spectrometry (ICP-MS) is used for the detection of ⁵²Cr (83.8%) species in ion chromatography (IC), interference from polyatomic ions such as ⁴⁰Ar¹²C⁺ and ³⁵Cl¹⁶O¹H⁺, often occurs due to their mass at m/z 52. To address the issue, an octopole reaction system (ORS) in ICP-MS, including He and H<inf>2</inf> modes, was used to determine whether the background and interference from polyatomic ions could be reduced in the detection of ⁵²Cr. Compared to standard mode, the polyatomic ions were reduced by either He or H<inf>2</inf>; for example, more than 97 and 98% of ³⁵Cl was removed using a He and H<inf>2</inf> tune, respectively. However, the detection sensitivity for ⁵²Cr was decreased, for example, the sensitivity was 27.95 and 67.02% of the standard mode for Cr(EDTA)<inf>2</inf> ^-using a He and H<inf>2</inf> tune, respectively. The H<inf>2</inf> tune is recommended for the detection of ⁵²Cr at a flow rate of 2.0 mL/min with detection limits in the range of 0.2-0.4 μg/L. The developed method was used to measure chromium speciation in waters containing high concentration of chloride. © 2007 Elsevier B.V. All rights reserved.enCopyright status unknownchromium speciationcollision reaction cellcontaminated waterIC-ICPMSJournal article10.1016/j.talanta.2007.05.030