Rehorek, S.Leigh, C.Firth, B.2006-06-232006-06-231999Copeia, 1999; 2(2):526-5280045-8511http://hdl.handle.net/2440/5348The squamate Harderian gland is a serous secreting structure located in the anterior aspect of the orbit. Active secretion is hitherto undescribed, and the mode of secretion is debatable. The authors in this study examined the rate of protein synthesis and secretion using autoradiography. Intraperitoneal injections of tritiated methiodine were administered to Australian skink lizard (Hemiergis decresiensis). The results revealed that two hours after the initial injection labeling was observed basely in the secretory cells of the Harderian gland. After 69 hours, the labeling was observed solely in the glandular lumina. Although this study does not determine the mechanism of secretion, it is the first to show that not only are proteins regularly produced and secreted by the skink Harderian gland but also that protein is produced and secreted within a three-day period.enJournal article0030006264001999125310.2307/14475050000802931000362-s2.0-003353203870270