Li, J.Schartner, E.Musolino, S.Quirk, B.Kirk, R.Ebendorff-Heidepriem, H.McLaughlin, R.2018-05-162018-05-162018Optics Letters, 2018; 43(8):1682-16850146-95921539-4794http://hdl.handle.net/2440/112112The ability to visualize structure whilst simultaneously measuring chemical or physical properties of a biological tissue has the potential to improve our understanding of complex biological processes. We report the first miniaturized single-fiber-based imaging+sensing probe capable of simultaneous optical coherence tomography (OCT) imaging and temperature sensing. An OCT lens is fabricated at the distal end of a double clad fiber, including a thin layer of rare-earth doped tellurite glass to enable temperature measurements. The high refractive index of the tellurite glass enables a common-path interferometer configuration for OCT, allowing easy exchange of probes for biomedical applications. The simultaneous imaging+sensing capability is demonstrated on rat brains.en© 2018 Optical Society of AmericaBrainAnimalsRatsDiagnostic ImagingTomography, Optical CoherenceBody TemperatureEquipment DesignFiber Optic TechnologyOptical FibersMiniaturized single-fiber-based needle probe for combined imaging and sensing in deep tissueJournal article003008596910.1364/OL.43.0016820004300845000152-s2.0-85045573412400188Li, J. [0000-0001-8818-6070]Schartner, E. [0000-0003-1669-4302]Musolino, S. [0000-0003-2429-574X]Ebendorff-Heidepriem, H. [0000-0002-4877-7770]McLaughlin, R. [0000-0001-6947-5061]