Anderson, J.Myers, J.Watson, D.Gabb, M.Mathew, G.Jamieson, G.2006-06-262006-06-261998Digestive Diseases and Sciences, 1998; 43(4):847-8530163-21161573-2568http://hdl.handle.net/2440/10123A prospective double-blind randomized trial wasinitiated to examine two types of laparoscopicfundoplication (Nissen and anterior). Thirty-twopatients with proven gastroesophageal reflux diseasepresenting for primary laparoscopic antireflux surgerywere randomized to undergo either Nissen fundoplication(N = 13) or anterior hemifundoplication (N = 19).Postoperative fluoroscopic and manometric examinationwas carried out concomitantly. Nissenfundoplication resulted in significantly greaterelevation of resting (33.5 vs 23 mm Hg) and residuallower esophageal sphincter pressures (17 vs 6.5 mm Hg)and lower esophageal ramp pressure (26 vs 20.5 mm Hg) than theanterior partial fundoplication. A smallerradiologically measured sphincter opening diameter wasseen following Nissen fundoplication (9 mm) comparedwith anterior fundoplication (12 mm). Lower esophageal ramppressure correlated weakly (r = 0.37, P = 0.04) withpostoperative dysphagia. It is concluded that the typeof fundoplication performed significantly influences postoperative manometric and video bariumradiology outcomes. The clinical relevance of thisrequires further investigation.enEsophagogastric JunctionHumansGastroesophageal RefluxBarium SulfateContrast MediaFluoroscopyLaparoscopyFundoplicationPostoperative PeriodProspective StudiesDouble-Blind MethodManometryDeglutitionPressureVideotape RecordingMiddle AgedFemaleMaleJournal article0030004645001998115110.1023/A:10188866027520000730721000242-s2.0-003190202368651Myers, J. [0000-0003-2157-7098]