Kahawita, S.Casson, R.2019-05-012019-05-012014Canadian Journal of Ophthalmology, 2014; 49(1):35-390008-41821715-3360http://hdl.handle.net/2440/118712Objective: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). Methods: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). Results: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09–1.88). Conclusions: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation.enCrown Copyright © 2014 Published by Elsevier Inc on behalf of the Canadian Ophthalmological Society. All rights reserved.Platelet Aggregation InhibitorsJournal article003001524610.1016/j.jcjo.2013.07.0160003311503000212-s2.0-84901333504110586Casson, R. [0000-0003-2822-4076]