Dent, E.Woo, J.Scott, D.Hoogendijk, E.O.2021-08-302021-08-302021European Journal of Internal Medicine, 2021; 90:1-90953-62051879-0828http://hdl.handle.net/2440/131697Sarcopenia is a disease related to accelerated loss of skeletal muscle and subsequent decline in functional capacity. It affects approximately 13% of the world's population aged over 60 years. Sarcopenia is primarily managed and prevented through a combination of exercise prescription combined with appropriate nutritional strategies. This review outlines diagnostic and case finding/screening tools for age-related (primary) sarcopenia used in research and clinical practice. Diagnostic tools critically reviewed include those of the: European Workgroup for Sarcopenia (EWGSOP) versions 1 and 2; Asian Working Group for Sarcopenia (AWGS) versions 1 and 2; Foundation for the National Institutes of Health (FNIH); and the Sarcopenia Definition and Outcomes Consortium (SDOC). Criteria used by diagnostic tools (muscle mass, muscle strength and physical functioning/performance) are also detailed. Case-finding tools include the SARC-F questionnaire, Ishii's formula and Goodman's screening grid. Additionally, this review discusses the strengths and weaknesses of each diagnostic and case-finding tool, and examines their ability to reliably predict adverse clinical outcomes and patient responses to potential therapies.en© 2021 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.Aged; 80 and over; sarcopenia; geriatric assessment/methodsJournal article100004536810.1016/j.ejim.2021.06.0030006816035000012-s2.0-85111378020581959Dent, E. [0000-0002-4006-3992]