Chen, L.Meng, Q.Chen, Y.Smales, R.Yip, K.2009-11-182009-11-182008Journal of Dentistry, 2008; 36(9):697-7020300-57121879-176Xhttp://hdl.handle.net/2440/53483Copyright © 2008 Elsevier Ltd All rights reserved.<h4>Aim</h4>To evaluate the effect of fluoride iontophoresis on the microtensile bond strength (MTBS) between coronal dentin and two resin-based adhesive systems, and to measure quantitatively dentinal tubule occlusion.<h4>Methods</h4>Twelve freshly extracted intact human mandibular third molars were divided randomly into four groups. The superficial occlusal dentin of each tooth was exposed and treated. Group A1: One-Step Plus total-etch adhesive system; group A2: One-Step Plus total-etch adhesive system after fluoride iontophoresis; group B1: ACE BOND SE self-etching adhesive system; group B2: ACE BOND SE self-etching adhesive system after fluoride iontophoresis. A resin composite buildup was made for each tooth, which was then sectioned along its long axis to produce 10 beams (1.0 mm x 1.0 mm) for the microtensile bond strength (MTBS) test. Five dentin disks were cut in half and their occlusal surfaces etched with 6% citric acid. The test halves were treated with fluoride iontophoresis. Four SEM photomicrographs were taken from corresponding sites on each test and each non-treated control half-disk. Image-Pro Plus 4 software quantified the percentage of tubule occlusion. Data were analyzed using one-way ANOVA, chi(2)- and t-tests, with the probability level set at alpha=0.05.<h4>Results</h4>The mean MTBS (MPa) for each group was, A1: 30.86 (S.D. 6.84); A2: 25.04 (8.49); B1: 19.22 (6.88); B2: 19.40 (6.92). There were significant differences among all groups (P < or = 0.02), except between groups B1 and B2 (P=0.92). Fluoride iontophoresis resulted in significantly increased dentinal tubule occlusion (P<0.001).<h4>Conclusions</h4>Fluoride iontophoresis treatment reduced significantly the dentin bond strength of One-Step Plus total-etch adhesive, but not that of ACE BOND SE self-etching adhesive. However, the bond strength of the former remained significantly higher than that of the latter adhesive system.enMolarDentinHumansDentin SensitivityFluoridesResin CementsCariostatic AgentsDentin-Bonding AgentsMicroscopy, Electron, ScanningIontophoresisAnalysis of VarianceDental BondingAcid Etching, DentalDental Stress AnalysisSurface PropertiesTensile StrengthJournal article002008304710.1016/j.jdent.2008.04.0180002596592000052-s2.0-4854909173541717