Crawford, G.B.Dzierżanowski, T.Hauser, K.Larkin, P.Luque-Blanco, A.I.Murphy, I.Puchalski, C.M.Ripamonti, C.I.2021-08-232021-08-232021ESMO Open, 2021; 6(4):100225-1-100225-132059-70292059-7029http://hdl.handle.net/2440/131574• This ESMO Clinical Practice Guideline provides key recommendations for end-of-life care for patients with advanced cancer. • It details care that is focused on comfort, quality of life and approaching death of patients with advanced cancer. • All recommendations were compiled by a multidisciplinary group of experts. • Recommendations are based on available scientific data and the authors’ collective expert opinion.en© 2021 The Authors. Published by Elsevier Ltd on behalf of European Society for Medical Oncology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).end of life; cancer patient; total care; death and dying; palliative care; clinical practice guidelineJournal article100004605210.1016/j.esmoop.2021.100225585499Crawford, G.B. [0000-0001-7347-8855]