Misso, M.L.Tassone, E.C.Costello, M.F.Dokras, A.Laven, J.Moran, L.J.Teede, H.J.2019-02-052019-02-052018Seminars in Reproductive Medicine, 2018; 36(1):28-341526-80041526-4564http://hdl.handle.net/2440/117612The evidence-based guideline for the assessment and management of polycystic ovary syndrome (PCOS) integrates the best available evidence with international, multidisciplinary clinical expertise and consumer preferences to provide health professionals, consumers, and policy makers with high-quality, comprehensive guidance about diagnosing and managing PCOS. Here, we outline the rigorous and systematic process, defined a priori and documented to be reproducible, to minimize bias and maintain transparency, in alignment with the Appraisal of Guidelines for Research and Evaluation (AGREE II) criteria and incorporating the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework that render this PCOS evidence-based guideline credible, trustworthy, reliable, and useable.enCopyright © 2018 by Thieme Medical Publishers, Inc.Polycystic ovary syndrome; evidence-based guidelines; AGREE II; GRADE; methodologyLarge-scale evidence-based guideline development engaging the international PCOS communityJournal article003010131910.1055/s-0038-16673120004444566000062-s2.0-85053280854438382Moran, L.J. [0000-0001-5772-6484]Teede, H.J. [0000-0001-7609-577X]