Hidayat, I.Preston, C.2007-05-112007-05-112001Pesticide Biochemistry and Physiology, 2001; 71(3):190-1950048-3575http://hdl.handle.net/2440/27773Copyright © 2001 Elsevier Science (USA). All rights reserved.A population of Digitaria sanguinalis selected by and resistant to the acetyl-coenzyme A carboxylase-inhibiting herbicide fluazifop-P-butyl is cross-resistant to the acetolactate synthase (ALS) inhibitor imazethapyr. The resistant population was six-fold resistant to imazethapyr despite never having been exposed to any ALS-inhibiting herbicide. ALS activity extracted from the resistant population was susceptible to imidazolinone herbicides. Malathion, a known cytochrome P450 monooxygenase inhibitor, synergized imazethapyr activity on the resistant population, suggesting that resistance is due to increased herbicide metabolism. In contrast, malathion antagonized fluazifop-P-butyl activity. Therefore, it is likely that the enzyme responsible for fluazifop acid detoxification in D. sanguinalis is different from the enzyme that detoxifies imazethapyr.enJournal article002001190810.1006/pest.2001.25760001733683000072-s2.0-003569267661167Preston, C. [0000-0002-7588-124X]