Kortschak, R.Tucker, P.Saint, R.2007-05-112007-05-112000Trends in Biochemical Sciences, 2000; 25(6):294-2990968-00041362-4326http://hdl.handle.net/2440/28004Copyright © 2000 Elsevier Science Ltd. All rights reserved.Members of the recently discovered ARID (AT-rich interaction domain) family of DNA-binding proteins are found in fungi and invertebrate and vertebrate metazoans. ARID-encoding genes are involved in a variety of biological processes including embryonic development, cell lineage gene regulation and cell cycle control. Although the specific roles of this domain and of ARID-containing proteins in transcriptional regulation are yet to be elucidated, they include both positive and negative transcriptional regulation and a likely involvement in the modification of chromatin structure.enDNA-binding proteinTranscription factorChromatinDevelopmentEvolutionJournal article000100048610.1016/S0968-0004(00)01597-80000875280000102-s2.0-003421321763721Kortschak, R. [0000-0001-8295-2301]