Gentilcore, D.O'Donovan, D.Jones, K.Horowitz, M.2007-06-022007-06-022003Current Diabetes Reports, 2003; 3(5):418-4261534-48271539-0829http://hdl.handle.net/2440/33124The original publication is available at www.springerlink.com Copyright © 2003 by Current Science Inc.The management of diabetic gastroparesis often represents a significant clinical challenge in which the maintenance of nutrition is pivotal. Gastric emptying is delayed in 30% to 50% of patients with longstanding type 1 or type 2 diabetes and upper gastrointestinal symptoms also occur frequently. However, there is only a weak association between the presence of symptoms and delayed gastric emptying. Acute changes in blood glucose concentrations affect gastric motility in diabetes; hyperglycemia slows gastric emptying whereas hypoglycemia may accelerate it; blood glucose concentrations may also influence symptoms. It is now recognized that gastric emptying is a major determinant of postprandial glycemia and, therefore, there is considerable interest in the concept of modulating gastric emptying, by dietary or pharmacologic means, to optimize glycemic control in diabetes.enHumansGastroparesisAutonomic Nervous System DiseasesDiabetic NeuropathiesDiabetes ComplicationsBlood GlucoseGastric EmptyingJournal article002003189510.1007/s11892-003-0087-92-s2.0-024233513357875Jones, K. [0000-0002-1155-5816]Horowitz, M. [0000-0002-0942-0306]