Gulati, K.Aw, M.Findlay, D.Losic, D.2013-04-092013-04-092012Therapeutic Delivery, 2012; 3(7):857-8732041-59902041-6008http://hdl.handle.net/2440/76675Titania nanotube (TNT) arrays fabricated by electrochemical anodization of titanium are currently one of the most attractive nanomaterials due to their remarkable properties. In this review, we highlight recent research activities that are focused on the application of the TNT arrays for local drug delivery, specifically for addressing problems associated with orthopedic implants. The advantages of drug-releasing implants based on TNT arrays for local delivery of therapeutics in bone related to these challenging problems including inflammation, infection and osseointegration are discussed. An overview of recent research to advance the drug-releasing performance of TNT arrays and the potential of their future applications and development are presented.enCopyright status unknownBone and BonesAnimalsHumansBone DiseasesTitaniumIntercellular Signaling Peptides and ProteinsAnti-Inflammatory AgentsBiocompatible MaterialsDrug ImplantsDrug CarriersAnti-Infective AgentsTechnology, PharmaceuticalDrug CompoundingOsseointegrationChemistry, PharmaceuticalNanotubesNanomedicineLocal drug delivery to the bone by drug-releasing implants: perspectives of nano-engineered titania nanotube arraysJournal article002012148010.4155/tde.12.662-s2.0-8486463224623442Losic, D. [0000-0002-1930-072X]