Hitchman, L.Machin, M.Ambler, G.Benson, R.Birmpili, P.Blair, R.Bosanquet, D.Dattani, N.Dovell, G.Forsythe, R.Gwilym, B.Machin, M.Nandhra, S.Onida, S.Preece, R.Salim, J.S.Saratzis, T.Shalhoub,Singh, A.Argus, L.et al.2025-07-092025-07-092021Journal of Cardiovascular Surgery, 2021; 62(6):558-5700021-95091827-191Xhttps://hdl.handle.net/2440/145782Background: The COVIDSurg collaborative was an international multicenter prospective analysis of perioperative data from 235 hospitals in 24 countries. It found that perioperative COVID-19 infection was associated with a mortality rate of 24%. At the same time, the COVER study demonstrated similarly high perioperative mortality rates in vascular surgical patients undergoing vascular interventions even without COVID-19, likely associated with the high burden of comorbidity associated with vascular patients. This is a vascular subgroup analysis of the COVIDSurg cohort. Methods: All patients with a suspected or confirmed diagnosis of COVID-19 in the 7 days prior to, or in the 30 days following a vascular procedure were included. The primary outcome was 30-day mortality. Secondary outcomes were pulmonary complications (adult respiratory distress syndrome, pulmonary embolism, pneumonia and respiratory failure). Logistic regression was undertaken for dichotomous outcomes. Results: Overall, 602 patients were included in this subgroup analysis, of which 88.4% were emergencies. The most common operations performed were for vascular-related dialysis access procedures (20.1%, N.=121). The combined 30-day mortality rate was 27.2%. Composite secondary pulmonary outcomes occurred in half of the vascular patients (N.=275, 45.7%). Conclusions: Mortality following vascular surgery in COVID positive patients was significantly higher than levels reported pre-pandemic, and similar to that seen in other specialties in the COVIDSurg cohort. Initiatives and surgical pathways that ensure vascular patients are protected from exposure to COVID-19 in the peri-operative period are vital to protect against excess mortality.en© 2021 Edizioni Minerva MedicaCOVID-19; Vascular surgical procedures; Health care outcome assessment.HumansVascular DiseasesTreatment OutcomeVascular Surgical ProceduresRisk AssessmentRisk FactorsProspective StudiesTime FactorsAdolescentAdultAgedAged, 80 and overMiddle AgedChildChild, PreschoolInfantFemaleMaleYoung AdultPatient SafetyGlobal HealthOutcome and Process Assessment, Health CareCOVID-19Journal article10.23736/S0021-9509.21.12024-52024-02-12683074