Honen, Bonny2006-12-282006-12-2820032003http://hdl.handle.net/2440/22003Author's previous publications inserted.Bibliography: leaves 136-147.147 leaves : ill. ; 30 cm.It is well recognized that the consumption of fish correlates with a reduction in mortality due to cardiovascular disease. Whole heart studies have identified that dietary fish oil confers protection from cardiac arrhythmias. However, not all arrhythmias arise from disturbances in membrane electrical excitability, a class of arrhythmias arise from calcium mishandling. The aim of this thesis was to determine whether the antiarrhythmic actions of polyunsaturated fatty acids present in fish oil are due to modulation of calcium handling.197435 bytesapplication/pdfenThesis