Shan, J.Ye, C.Jiang, Y.Jaroniec, M.Zheng, Y.Qiao, S.-Z.2022-05-252022-05-252022Science Advances, 2022; 8(17)2375-25482375-2548https://hdl.handle.net/2440/135199Single-atom catalysts (SACs) include a promising family of electrocatalysts with unique geometric structures. Beyond conventional ones with fully isolated metal sites, an emerging class of catalysts with the adjacent metal single atoms exhibiting intersite metal-metal interactions appear in recent years and can be denoted as correlated SACs (C-SACs). This type of catalysts provides more opportunities to achieve substantial structural modification and performance enhancement toward a wider range of electrocatalytic applications. On the basis of a clear iden-tification of metal-metal interactions, this review critically examines the recent research progress in C-SACs. It shows that the control of metal-metal interactions enables regulation of atomic structure, local coordination, and electronic properties of metal single atoms, which facilitate the modulation of electrocatalytic behavior of C-SACs. Last, we outline directions for future work in the design and development of C-SACs, which is indispensable for creating high-performing new SAC architectures.enCopyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC)Journal article10.1126/sciadv.abo07622022-05-25610821Shan, J. [0000-0003-4308-5027]Jiang, Y. [0000-0002-7545-2891]Zheng, Y. [0000-0002-2411-8041]Qiao, S.-Z. [0000-0002-1220-1761] [0000-0002-4568-8422]