Harkin, Louise Anne2018-03-162018-03-162004http://hdl.handle.net/2440/111086Overall aim was to determine if the accumulation of deleted mtDNA molecules in tissues during the normal aging process is confined to the human, or whether it is a phenomenon also shared by other species. The aging mouse was selected as an experimental model.enAging -- Molecular aspects; Cells -- Aging; Geriatrics; Mice -- CytologyPCR analysis of the mouse mitochondrial genome to assess whether deletions accumulate with ageTheses